¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ scientists have shown how the brain’s ability to clear out toxic proteins is impaired in Huntington’s disease and other forms of dementia – and how, in a study in mice, a repurposed HIV drug was able to restore this function, helping prevent this dangerous build-up and slowing progression of the disease.
A new mechanism that stops the progression of Huntington’s disease in cells has been identified by scientists at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ and UCL, as part of their research groups at the UK Dementia Research Institute.
A prescription drug to treat high blood pressure has shown promise against conditions such as Parkinson’s, Huntington’s and forms of dementia in studies carried out in mice and zebrafish at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ.
Sheep can be trained to recognise human faces from photographic portraits – and can even identify the picture of their handler without prior training – according to new research from scientists at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ.
Scientists at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ will this week begin studying sheep that have been genetically modified to carry the mutation that causes Huntington’s disease. The sheep are believed to be the first Merinos to have been imported into the UK from Australia for about 50 years.
Early warning signs of Huntington’s disease have been uncovered in a sheep carrying the human disease-causing genetic variant, providing new insights into this devastating illness, a new study in Scientific Reports has found.
How does the brain make connections, and how does it maintain them? ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ neuroscientists and mathematicians are using a variety of techniques to understand how the brain ‘wires up’, and what it might be able to tell us about degeneration in later life.
Sheep are smarter than we might think, with brains surprisingly similar to ours. These similarities are helping researchers to study a devastating and incurable infant brain disease.
New research from scientists at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ provides critical insight into the formation of autophagosomes, which are responsible for cleaning up cellular waste.
Scientists at the ¹ú¼ÊÃ×À¼¶ÔÕó¿ÆĪ have discovered that sheep are more intelligent than previously believed.
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