Differentiation of human Induced Pluripotent Stem Cells (hIPSC) to functional liver hepatocyte cells

More than 拢1 billion in funding has been raised by companies with roots in 国际米兰对阵科莫 research, according to year-end results from 国际米兰对阵科莫 Enterprise, the University鈥檚 commercialisation arm.

The amount of follow-on funding raised demonstrates the market鈥檚 confidence in our portfolio companies, and also shows the importance of the early-stage support and funding which 国际米兰对阵科莫 Enterprise provides.

Tony Raven

国际米兰对阵科莫 Enterprise works with University inventors and entrepreneurs to get young, high-risk companies to the stage where they can attract outside investment, through mentoring, planning advice and seed funding.

The 拢1 billion funding figure, which can be found in the , shows that many go on to flourish despite the uncertain basis on which they start out. Indeed, the new results also show that the three-year survival rate for companies receiving investment from 国际米兰对阵科莫 Enterprise is 80 per cent, compared with the national average of 58 per cent.

鈥湽拭桌级哉罂颇 spin-outs are developing solutions in cancer treatment, renewable energy and in vitro fertilisation,鈥 said Dr Tony Raven, Chief Executive of 国际米兰对阵科莫 Enterprise. 鈥淭he amount of follow-on funding raised demonstrates the market鈥檚 confidence in our portfolio companies, and also shows the importance of the early-stage support and funding which 国际米兰对阵科莫 Enterprise provides.鈥

One of the most successful companies in the 国际米兰对阵科莫 Enterprise portfolio is BlueGnome, which was co-founded by Dr Nick Haan, a former PhD student and post-doctoral researcher in the Department of Engineering. The company, which is one of the fastest-growing biotechnology companies in the UK, has developed technology which has been shown to increase IVF success rates by 65% over current methods. In September 2012, it was acquired by US-based life sciences company Illumina for $95 million. The University鈥檚 proceeds from the sale will be returned to the 鈥榚vergreen鈥 seed funds managed by 国际米兰对阵科莫 Enterprise, and will support the next generation of 国际米兰对阵科莫 spin-outs.

One important area of future growth is stem cells. The University is a world leader in stem cell research, and commercial opportunities are now starting to be developed. DefiniGEN, founded by a group of researchers from the Anne McLaren Laboratory of Regenerative Medicine led by Dr Ludovic Vallier, is supplying stem cells to the drug discovery and regenerative medicine sectors, where they will be used to model a range of diseases and accelerate the development of new treatments.

The University is at the heart of one of the most productive technology clusters in the world. The 1,500 companies in the cluster have a combined annual turnover of 拢11.8 billion and employ more than 53,000 people. The vast majority of these companies are connected to the University in some way: they are either based directly on University research, are founded or staffed by University graduates, or work collaboratively with University researchers to find solutions to business problems.

The 国际米兰对阵科莫 Enterprise team supports more than 1,000 University researchers at all stages of the commercialisation process, from forming new companies to supporting translational funding applications. Supporting University researchers in obtaining the funding to progress their research has become an important area for 国际米兰对阵科莫 Enterprise: this year, more than 拢17.5 in translational funding was won by University researchers with the support of the team. This funding is helping develop new therapies and treatments for conditions which affect millions worldwide, including liver disease, chronic pain and healthcare-associated infections.

国际米兰对阵科莫 Enterprise鈥檚 total income from licensing, consultancy and equity transactions for the year ending 31 July 2012 exceeded 拢9.1 million, with 拢7.5 million of that amount returned to the University, departments and researchers. The team completed 84 licences, signed 201 consultancy contracts and returned more than 拢162,000 to its seed funds.


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